Eirene Putri Gracia, Waruwu (2026) PROFIL PENGGUNAAN OBAT PADA PASIEN GAGAL GINJAL KRONIS DI RUMAH SAKIT UNS SURAKARTA TAHUN 2025. Diploma thesis, Universitas Setia Budi.
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Abstract
Gagal Ginjal Kronis (GGK) merupakan gangguan fungsi ginjal
yang berlangsung progresif dan irreversible sehingga membutuhkan
terapi jangka panjang. Pasien GGK umumnya menggunakan berbagai
jenis obat untuk mengatasi penyakit utama maupun penyakit penyerta,
sehingga berpotensi memengaruhi outcome terapi. Penelitian ini
bertujuan mengetahui profil penggunaan obat, obat yang paling banyak
digunakan, serta hubungan pola penggunaan obat dengan outcome
terapi pasien GGK di Rumah Sakit UNS Surakarta tahun 2025.
Penelitian ini merupakan penelitian non-eksperimental dengan
desain deskriptif analitik dan pendekatan retrospektif menggunakan
data rekam medis pasien GGK rawat inap periode Januari–Desember
2025. Pengambilan sampel dilakukan dengan teknik purposive
sampling dan diperoleh 232 pasien yang memenuhi kriteria inklusi.
Analisis data dilakukan menggunakan distribusi frekuensi dan
persentase serta uji Chi-Square.
Hasil penelitian menunjukkan pasien GGK lebih banyak
berjenis kelamin perempuan (56%), berusia >30 tahun (98%), dan
stadium V merupakan stadium terbanyak (78%). Obat yang paling
banyak digunakan yaitu asam folat (13,1%), amlodipin (11,7%), dan
ondansetron (10,2%). Outcome terapi menunjukkan 98,71% pasien
mengalami perbaikan kondisi klinis. Hasil uji Chi-Square menunjukkan
terdapat hubungan signifikan antara pola penggunaan obat dengan
outcome terapi (p<0,05).
Kata kunci: Gagal ginjal kronis, profil penggunaan obat, pola terapi,
Outcome terapi, retrospektif.
Chronic Kidney Disease (CKD) is a progressive and irreversible
impairment of kidney function that requires long-term therapy. CKD
patients generally receive various medications to manage the primary
disease and comorbidities, which may affect therapeutic outcomes. This
study aimed to determine the drug utilization profile, the most
frequently used medications, and the relationship between drug use
patterns and therapeutic outcomes in CKD patients at UNS Hospital
Surakarta in 2025.
This study was a non-experimental study with a descriptive
analytic design and a retrospective approach using medical record data
of hospitalized CKD patients during January–December 2025. The
sampling technique used was purposive sampling, with a total of 232
patients who met the inclusion criteria. Data analysis was performed
using frequency distribution and percentage analysis, as well as the
Chi-Square test
The results showed that CKD patients were predominantly
female (56%), aged >30 years (98%), and CKD stage V was the most
common stage (78%). The most frequently used medications were folic
acid (13.1%), amlodipine (11.7%), and ondansetron (10.2%).
Therapeutic outcomes showed that 98.71% of patients experienced
clinical improvement. The Chi-Square test results indicated a
significant relationship between drug use patterns and therapeutic
outcomes (p<0.05).
| Item Type: | Thesis (Diploma) |
|---|---|
| Uncontrolled Keywords: | Gagal ginjal kronis, profil penggunaan obat, pola terapi, Outcome terapi, retrospektif. Chronic renal failure, drug use profile, therapy pattern, therapy Outcome, retrospective. |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RS Pharmacy and materia medica |
| Divisions: | Universitas Setia Budi > Fakultas Farmasi > D3 Farmasi |
| Depositing User: | Unnamed user with email baa.si@setiabudi.ac.id |
| Date Deposited: | 27 Jul 2026 07:24 |
| Last Modified: | 27 Jul 2026 07:24 |
| URI: | https://eprints.setiabudi.ac.id/id/eprint/574 |
