ANJANI, GARNISYA LOKOVINKA (2025) PERBEDAAN KADAR GLUKOSA DARAH PADA PASIEN PRE DAN POST HEMODIALISIS DI RUMAH SAKIT UNS SURAKARTA. Diploma thesis, Universitas Setia Budi.
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Abstract
Hemodialisis merupakan metode penggantian fungsi ginjal untuk
menyaring darah, terutama pada pasien dengan Gagal Ginjal Kronik
(GGK). Salah satu komplikasi yang sering terjadi pada pasien
hemodialisis adalah perubahan kadar glukosa darah. Penelitian ini
bertujuan untuk mengetahui perbedaan kadar glukosa darah sebelum dan
sesudah hemodialisis pada pasien di Rumah Sakit UNS Surakarta.
Penelitian ini menggunakan desain observasional analitik dengan
pendekatan cross sectional. Waktu yang dilakukan pada bulan Februari
hingga April 2025, besar populasi sebanyak 78 responden yang dipilih
dengan teknik simple random sampling. Data kadar glukosa diukur
menggunakan metode POCT (Point of Care Testing) sebelum dan
sesudah hemodialisis. Teknik analisis data menggunakan uji statistik
kolmogrov smirnov dan dilanjutkan uji beda yang digunakan Mann-
Whitney.
Hasil uji menunjukkan terdapat perbedaan kadar glukosa darah
antara pre dan post hemodialisis. Nilai rerata kadar glukosa darah
sebelum hemodialisis adalah 157± 80 mg/dL dan setelah hemodialisis
menurun menjadi 125,5 ± 38 mg/dL. Didapatkan hasil uji normalitas
(Kolmogorov Smirnov) pada kadar glukosa darah pre HD p-value
sebesar 0,001 dan kadar glukosa daeah post HD p-value sebesar 0,037
data dikatakan tidak berdistribusi normal dan dilanjutkan uji beda
menggunakan (Mann-Whitney) didapatkan hasil p-value kadar glukosa
darah pre dan post HD sebesar 0,038 maka hipotesis dapat diterima. Dari
penelitian ini dapat disimpulkan terdapat perbedaan yang bermakna pada
kadar glukosa darah pasien pre dan post hemodialisis di RS UNS
Surakarta. Penurunan kadar glukosa ini dapat disebabkan oleh proses
difusi glukosa ke dalam cairan dialisat selama hemodialisis. Oleh karena
itu, pemantauan kadar glukosa darah secara rutin pada pasien
hemodialisis sangat diperlukan untuk mencegah komplikasi seperti
hipoglikemia.
Hemodialysis is a kidney replacement therapy used to filter the
blood, particularly in patients with Chronic Kidney Disease (CKD). One
of the common complications in hemodialysis patients is a change in
blood glucose levels. This study aims to determine the difference in blood
glucose levels before and after hemodialysis in patients at UNS Hospital
Surakarta.
This study used an analytical observational design with a cross-
sectional approach. The research was conducted from February to April
2025, involving a population of 78 respondents selected using a simple
random sampling technique. Blood glucose levels were measured using
the POCT (Point of Care Testing) method before and after hemodialysis.
Data analysis was performed using the Kolmogorov-Smirnov statistical
test, and the Mann-Whitney test is used as the follow-up comparative
test.
The test results showed a difference in blood glucose levels
between pre- and post-hemodialysis. The mean blood glucose level
before hemodialysis was 157 ± 80 mg/dL, which decreased to 125.5 ± 38
mg/dL after hemodialysis. The normality test (Kolmogorov-Smirnov)
showed a p-value of 0.001 for pre-hemodialysis blood glucose levels and
0.037 for post-hemodialysis, indicating that the data were not normally
distributed. Therefore, a non-parametric test (Mann-Whitney) was used,
yielding a p-value of 0.038 for the difference in blood glucose levels
before and after hemodialysis, which supports the hypothesis. Based on
this study, it can be concluded that there is a significant difference in
blood glucose levels between pre- and post-hemodialysis patients at UNS
Hospital Surakarta. The decrease in glucose levels may be due to the
diffusion of glucose into the dialysate fluid during the hemodialysis
process. Therefore, routine monitoring of blood glucose levels in
hemodialysis patients is essential to prevent complications such as
hypoglycemia.
| Item Type: | Thesis (Diploma) |
|---|---|
| Uncontrolled Keywords: | Glukosa Darah, Pre Hemodialisis, Post Hemodialisis Blood Glucose, Pre Hemodialysis, Post Hemodialysis |
| Subjects: | Q Science > Q Science (General) R Medicine > R Medicine (General) R Medicine > RA Public aspects of medicine |
| Divisions: | Universitas Setia Budi > Fakultas Ilmu Kesehatan > D4 Analis Kesehatan |
| Depositing User: | Unnamed user with email baa.si@setiabudi.ac.id |
| Date Deposited: | 30 Dec 2025 00:46 |
| Last Modified: | 30 Dec 2025 00:46 |
| URI: | https://eprints.setiabudi.ac.id/id/eprint/165 |
