Kasman, Firdah Rianty (2025) FORMULASI DAN UJI AKTIVITAS KRIM ANTI AGING EKSTRAK BUNGA ROSELLA (HibiscussabdariffaL) PADA KULIT PUNGGUNG KELINCI NEW ZEALAND YANG DIPAPAR SINAR UV-A. Other thesis, Universitas Setia Budi.
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Abstract
Bunga rosella memilki senyawa asam organik, fitosterol,
polifenol, antosianin, serta vitamin dan mineral. Antosianin merupakan
senyawa yang berkhasiat antioksidan, yakni meneralisir radikal bebas.
Tujuan penelitian ini adalah untuk mengetahui kemampuan, mutu fisik
serta formulasi krim anti aging terbaik ekstrak buga rosella.
Penelitian ini merupakan penelitin eksperimental di mana
tahapan yang dilakukan antara lain ekstraksi bunga rosella
menggunakan metode maserasi dengan pelarut etanol 70%, kemudian
diuapkan dengan rotavapor hingga didapatkan ekstrak kental. Formula
sediaan krim bunga rosella yang dibuat meliputi F1;F2;F3 dan F4, dan
pembuatan krim. Uji mutu fisik dilakukan pada semua formula sediaan
krim yang dibuat. Kemudian pengujian iritasi primer dilakukan dengan
cara memberikan krim pada punggung kelinci yang sudah dicukur dan
diaklimatisasi, pengkajian ini dilakukan selama 3 hari. Uji aktivitas
antiaging dilakukan pada kelinci dengan menggunakan skin analyzer
Variasi krim antiaging ekstrak bunga rosella mempengaruhi pH
dan stabilitas warna namun tidak mempengaruhi viskositas. Pengujian
keamanan sediaan tidak mengiritasi. Konsentrasi pada uji aktivitas anti�aging terbaik adalah krim ekstrak bunga rosella konsentrasi 1.5%.
.
Rosella flowers contain organic acid compounds, phytosterols,
polyphenols and anthocyanins, as well as vitamins and minerals.
Anthocyanins are compounds that have antioxidant properties, namely
neutralizing free radicals. The aim of this research is to determine the
ability, physical quality and formulation of the best rosella flea extract
anti-aging cream.
This research is an experimental research where the stages
carried out include extracting rosella flowers using the maceration
method with 70% ethanol solvent, then evaporating using a rotary
evaporator until a thick extract is obtained. The Rosella flower cream
preparation formula includes F1; F2; F3 and F4, and make cream.
Physical quality tests are carried out on all cream preparation formulas
made. Then a primary irritation test was carried out by applying cream
to the back of a rabbit that had been shaved and acclimatized. This test
is carried out for 3 days. Antiaging activity tests were carried out on
rabbit using a skin analyzer.
Variations in antiaging cream with rosella flower extract affect
pH and color stability but do not affect viscosity. Safety testing of non�irritating preparations. The best concentration in the anti-aging activity
test was rosella flower extract cream with a concentration of 1.5%.
| Item Type: | Thesis (Other) |
|---|---|
| Uncontrolled Keywords: | Hibiscus sabdariffa L, Anti Aging, Cream, Physical Quality, Irritation Test. Hibiscus sabdariffa L, Anti Aging, Krim, Mutu Fisik, Uji Iritasi. |
| Subjects: | Q Science > Q Science (General) Q Science > QK Botany Q Science > QL Zoology R Medicine > R Medicine (General) R Medicine > RS Pharmacy and materia medica R Medicine > RV Botanic, Thomsonian, and eclectic medicine |
| Divisions: | Universitas Setia Budi > Fakultas Farmasi > S1 Farmasi |
| Depositing User: | Unnamed user with email baa.si@setiabudi.ac.id |
| Date Deposited: | 02 Jan 2026 08:16 |
| Last Modified: | 02 Jan 2026 08:16 |
| URI: | https://eprints.setiabudi.ac.id/id/eprint/215 |
