PENGARUH VARIASI KONSENTRASI PVA DAN HPMC TERHADAP MUTU FISIK MASKER GEL PEEL-OFF EKSTRAK KULIT BUAH MANGGIS (Garcinia mangostana L.) SEBAGAI ANTIOKSIDAN

Anggi, Pravita (2023) PENGARUH VARIASI KONSENTRASI PVA DAN HPMC TERHADAP MUTU FISIK MASKER GEL PEEL-OFF EKSTRAK KULIT BUAH MANGGIS (Garcinia mangostana L.) SEBAGAI ANTIOKSIDAN. Other thesis, Universitas Setia Budi.

[thumbnail of INTISARI dan ABSTRACT.pdf] Text
INTISARI dan ABSTRACT.pdf

Download (110kB)
[thumbnail of FORM PUBLIKASI.pdf] Text
FORM PUBLIKASI.pdf

Download (401kB)
[thumbnail of AHNESA SURAT 17 OKT.pdf] Text
AHNESA SURAT 17 OKT.pdf

Download (39kB)
[thumbnail of COVER - BAB I.pdf] Text
COVER - BAB I.pdf

Download (1MB)
[thumbnail of BAB II.pdf] Text
BAB II.pdf

Download (272kB)
[thumbnail of BAB  III.pdf] Text
BAB III.pdf

Download (458kB)
[thumbnail of BAB IV.pdf] Text
BAB IV.pdf
Restricted to Repository staff only

Download (452kB)
[thumbnail of BAB V.pdf] Text
BAB V.pdf
Restricted to Repository staff only

Download (106kB)
[thumbnail of DAFTAR PUSTAKA.pdf] Text
DAFTAR PUSTAKA.pdf
Restricted to Repository staff only

Download (118kB)
[thumbnail of LAMPIRAN.pdf] Text
LAMPIRAN.pdf
Restricted to Repository staff only

Download (698kB)

Abstract

Kulit buah manggis (Garcinia mangostana L.) mengandung senyawa xanthone sebagai antioksidan. Masker gel peel-off merupakan sediaan masker yang penggunaannya dapat dikelupas setelah mengering. PVA digunakan sebagai pembentukan lapisan film, sedangkan HPMC digunakan sebagai gelling agent. Tujuan penelitian ini adalah untuk mengetahui pengaruh variasi konsentrasi PVA dan HPMC dalam formulasi masker gel peel-off terhadap mutu fisik, stabilitas dan aktivitas antioksidannya. Kulit buah manggis dibuat ekstrak dengan metode maserasi dengan pelarut etanol 70%. Masker gel peel-off diformulasikan menjadi tiga formula berisi ekstrak (FI: PVA 10%, HPMC 1%; FII: PVA 12%, HPMC 1%; FIII: PVA 12%, HPMC 1,5%) dan satu kontrol basis (FIV: PVA 12%, HPMC 1,5%), dilakukan uji mutu fisik, stabilitas dan aktivitas antioksidan. Ekstrak dan formula diuji aktivitas antioksidannya menggunakan metode DPPH. Hasil penelitian dianalisis secara statistik. Hasil penelitian menunjukkan bahwa peningkatan konsentrasi PVA maupun HPMC meningkatkan viskositas dan daya lekat, mempercepat waktu mengering namun menurunkan daya sebar sediaan. Formulasi II merupakan sediaan terbaik yang menghasilkan sediaan masker gel peel-off dengan bentuk gel semi padat, berwarna coklat muda dengan bau khas ekstrak, nilai pH 6,58; viskositas 15.533,33 cps; daya sebar 5,3-6,2 cm; daya lekat 8,31 detik; waktu mengering 27,41 menit, IC50 100,6323 ppm dan nilai AAI 1,57. The mangosteen rind (Garcinia mangostana L.) contains xanthone compounds as antioxidants. Peel-off gel masks are mask preparations whose use can be exfoliated after drying. PVA is used as a film formation, while HPMC is used as a gelling agent. The purpose of this study was to determine the effect of variations in PVA and HPMC concentrations in peel-off gel mask formulations on their physical quality, stability and antioxidant activity. The mangosteen rind extracted by maceration method with 70% ethanol solvent. The peel-off gel mask is formulated into three extract filled formulas (FI: PVA 10%, HPMC 1%; FII: PVA 12%, HPMC 1%; FIII: PVA 12%, HPMC 1.5%) and one base control (FIV: PVA 12%, HPMC 1.5%), physical, stability and antioxidant quality tests were performed. The extract and formula were tested for antioxidant activity using the DPPH method. The results of the study were analyzed statistically The results showed that increasing the concentration of PVA and HPMC increased viscosity and adhesion, accelerated drying time but decreased the dispersion of the preparation. Formulation II is the best preparation that produces peel-off gel mask preparations in the form of semi-solid gel, light brown in color with a characteristic extract odor, pH value 6,58; viscosity 15.533,33 cps; dispersion 5,3-6,2 cm; adhesion 8,31 seconds; drying time 27,41 minutes, IC50 100,6323 ppm and AAI value 1,57.
Item Type: Thesis (Other)
Uncontrolled Keywords: antioksidan, kulit buah manggis, PVA, HPMC, masker gel peel-off antioxidant, mangosteen rind, PVA, HPMC, peel-off gel mask
Subjects: R Medicine > R Medicine (General)
R Medicine > RL Dermatology
R Medicine > RM Therapeutics. Pharmacology
R Medicine > RS Pharmacy and materia medica
Divisions: Universitas Setia Budi > Fakultas Farmasi > S1 Farmasi
Depositing User: Unnamed user with email baa.si@setiabudi.ac.id
Date Deposited: 20 Feb 2026 07:31
Last Modified: 20 Feb 2026 07:31
URI: https://eprints.setiabudi.ac.id/id/eprint/475

Actions (login required)

View Item
View Item