PENGARUH PROPORSI ASAM STEARAT DAN TEA TERHADAP MUTU FISIK SEDIAAN LOTION ANTIOKSIDAN EKSTRAK ETANOL KULIT BUAH MANGGIS (Garcinia mangostana L.)

Radiasi sinar ultraviolet yang berlebihan mampu memberikan dampak negatif pada kulit. Pencegahan dilakukan dengan menghindari sinar matahari berlebihan dan mengkonsumsi antioksidan. Kulit manggis (Garcinia mangostana L.) mengandung senyawa xanthone yang memiliki aktivitas sebagai penangkal radikal bebas. Tujuan penelitian ini adalah memformulasikan sediaan lotion ekstrak kulit manggis dengan proporsi asam stearat dan TEA . Ekstrak kulit manggis diformulasikan menjadi sediaan lotion dengan variasi proporsi asam sterat dan TEA (3% : 1%), (4% : 1,5%), (4% : 2%). Asam stearat dan trietanolamin digunakan bahan pengemulsi yang stabil. Sediaan lotion diuji mutu fisik (organoleptis, homogentias, pH, viskositas, daya sebar, daya lekat, dan uji tipe emulsi)dan uji stabilitas sediaan dengan metode cycling test. Sediann lotion diuji aktivitas antioksidan dengan metode DPPH. Hasil enelitian dianalisis dengan IBM SPSS statistics 21 One Way ANOVA dan Post Hoc. Hasil penelitian menunjukkan bahwa asam stearat dan TEA berpengaruh terhadap pH, viskositas, daya lekat, daya sebar. Formula 1 dengan konsentrasi asam stearat 3% dan TEA 1% merupakan sediaan terbaik yang menghasilkan lotion dengan bentuk semi padat, berwarna coklat, beraroma rossae, nilai pH 6,6. Viskositas 3,183 cPas, daya sebar 5,57-6,26 cm, daya lekat 1,31 detik, dan untuk IC50 101,008 ppm. Excessevie ultraviolet radiation has an imact on the skin. Prevention is done by avoiding excessive sunlight and consuming antioxidants. Mangosteen peel (Garcinia mangostana L.) contains xanthone compounds which have activity as free radical scavengers. The aim of this study was to formulate a mangosteen rind extract lotion with the roortions of stearic acid and TEA. Mangosteen peel (Garcinia mangostana L.) extract was formulation into a lotion preparation with the proportions of stearic acid and TEA (3% : 1%), (4% :1,5%), (4% :2%). Stearic acid and triethanolamine are used as stable emulsifying agents. The lotion preparations were tested for hysical quality (organoletic, homogeneity,pH, viscosity, sreadability, adhesion, and emulsion type test) and the stability test was carried out using the cycling test method. Lotion was tested for antioxidant activity with the DPPH method. The research results were analyzed using IBM SPSS statistics 21 One Way ANOVA and Post Hoc. The result showed that stearic acid ant TEA had an effect on lotion preparations. Formula 1 with a concentration of stearic acid and TEA (3% :1%) is the best preparation which produces a lotion in an semi-solid form, brown ic color, has a rosse scent, a pH velue of 6,6, viscosity 3,183 cPas., spreadability 5,57-6,26 cm, adhesion 1,31 seconds, and for IC50 101,008 ppm.